public struct Struct_INTERNET_PROXY_INFO
        {
            public int dwAccessType;
            public IntPtr proxy;
            public IntPtr proxyBypass;
        };        [DllImport("wininet.dll", SetLastError = true)]
        private static extern bool InternetSetOption(IntPtr hInternet,
        int dwOption,
        IntPtr lpBuffer,
        int lpdwBufferLength);        private void RefreshIESettings(string strProxy)
        {
            const int INTERNET_OPTION_PROXY = 38;
            const int INTERNET_OPEN_TYPE_PROXY = 3;
            Struct_INTERNET_PROXY_INFO struct_IPI;            // Filling in structure 
            struct_IPI.dwAccessType = INTERNET_OPEN_TYPE_PROXY;
            struct_IPI.proxy = Marshal.StringToHGlobalAnsi(strProxy);
            struct_IPI.proxyBypass = Marshal.StringToHGlobalAnsi("local");            // Allocating memory 
            IntPtr intptrStruct = Marshal.AllocCoTaskMem(Marshal.SizeOf(struct_IPI));            // Converting structure to IntPtr 
            Marshal.StructureToPtr(struct_IPI, intptrStruct, true);            bool iReturn = InternetSetOption(IntPtr.Zero, INTERNET_OPTION_PROXY, intptrStruct, Marshal.SizeOf(struct_IPI));
            
        }        private void SomeFunc()
        {
            RefreshIESettings("127.0.0.1:9666");
            //or RefreshIESettings("http://1.2.3.4:8080"); //both worked 
            //or RefreshIESettings("http=1.2.3.4:8080"); //both worked             webBrowser1.Navigate("http://www.ip138.com/");
            //webBrowser1.Refresh();
        } 在线等....